NCF4

Across TCGA cell cohorts, NCF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,078 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NCF4-associated GO terms across cancer lineages are Rab protein signal transduction, Macropinocytosis, and T cell mediated cytotoxicity. Each is linked with NCF4 in more than 6 cancer types. Because this analysis shows association rather than direction, both NCF4-to-partner and partner-to-NCF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab protein signal transduction grouped by NCF4-low versus NCF4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCF4→partner) and Y-score (partner→NCF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Rab protein signal transduction →	+0.180	+0.708	<.001	.001	3	7
BLOOD_Myeloma	Macropinocytosis →	+0.244	+3.121	.002	.001	3	7
URINARY_TRACT	T cell mediated cytotoxicity →	+0.149	+0.661	<.001	.001	3	6
PANCREAS	Maintenance of unfolded protein →	+0.110	+0.176	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of CD8-positive, alpha-beta T cell proliferation →	+0.183	+0.203	.002	.009	3	6
BLOOD_Leukemia	Regulation of forebrain neuron differentiation →	+0.105	+2.434	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,078 associations by consensus.

Rab protein signal transduction by NCF4 expression — URINARY_TRACT

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