NCF2

Across TCGA pan-cancer cohorts, NCF2 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated NCF2 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NCF2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NCF2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

COAD, UCEC, and GBM are the cancer types where NCF2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.872	1.000	.012	84	view →
UCEC	OS	Median	II,III,IV	1.000	0.628	.013	12	view →
GBM	DFS	Quartile	All	0.651	0.854	.021	7	view →
LUAD	DFS	Median	II,III,IV	0.255	0.803	.025	5	view →
CCRCC	DFS	Tertile	II,III,IV	1.000	0.851	.024	2	view →
HNSC	OS	Median	IV	0.935	0.720	.024	2	view →
PDAC	OS	Quartile	III,IV	0.362	1.000	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

NCF2–COAD (DFS)

Open the COAD breakdown →