NCF2

Across TCGA patient cohorts, NCF2 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCF2-associated genes across cancer lineages are GMP, Erythrocytes, and MEP. Each is linked with NCF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCF2-to-partner and partner-to-NCF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by NCF2-low versus NCF2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCF2→partner) and Y-score (partner→NCF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	GMP →	+0.115	+2.416	.001	.049	3	2
UCEC	Erythrocytes →	+0.021	+1.946	.025	.028	3	2
UCEC	MEP →	+0.023	+2.032	.030	.017	3	2
OV	CD4+ naive T-cells →	+0.009	+5.197	<.001	.039	3	1
UCEC	Class-switched memory B-cells →	-0.053	-3.629	.018	.001	3	1
SKCM	Endothelial cells →	-0.036	-2.049	.011	.018	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GMP by NCF2 expression — BLCA

Explore this box plot interactively →