NCF1

Across TCGA cell cohorts, NCF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,344 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NCF1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Negative regulation of mRNA processing. Each is linked with NCF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both NCF1-to-partner and partner-to-NCF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by NCF1-low versus NCF1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCF1→partner) and Y-score (partner→NCF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of myoblast fusion →	+0.120	+0.337	<.001	<.001	3	10
BREAST	Negative regulation of myoblast fusion →	+0.132	+0.351	<.001	<.001	3	10
BREAST	Negative regulation of mRNA processing →	+0.075	+0.211	.002	.009	3	10
URINARY_TRACT	Cell-substrate junction assembly →	+0.171	+0.383	<.001	.003	2	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA catabolic process →	+0.066	+1.150	<.001	.004	3	9
OESOPHAGUS	Hemidesmosome assembly →	+0.208	+0.336	.002	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,344 associations by consensus.

Regulation of myoblast fusion by NCF1 expression — BREAST

Explore this box plot interactively →