NCF1

Across TCGA cell cohorts, NCF1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NCF1-associated genes across cancer lineages are MYOCD, SLC9C1, and COX8C. Each is linked with NCF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCF1-to-partner and partner-to-NCF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOCD grouped by NCF1-low versus NCF1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCF1→partner) and Y-score (partner→NCF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYOCD →	+1.296	+3.623	<.001	.007	3	1
BLOOD_Leukemia	SLC9C1 →	+0.145	+3.551	<.001	.008	3	1
BLOOD_Leukemia	COX8C →	+1.146	+3.544	<.001	.008	2	1
BLOOD_Leukemia	LMLN2 →	+0.023	+3.623	.009	.007	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MYOCD by NCF1 expression — BLOOD_Leukemia

Explore this box plot interactively →