NCEH1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NCEH1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NCEH1 data layer compared with 22 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NCEH1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NCEH1 expression acts as an unfavorable survival marker.

UCEC and READ are the cancer types where NCEH1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianIV0.2250.772<.00112view →
READOSMedianAll0.5270.932.0431view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NCEH1–UCEC (OS)

Kaplan–Meier survival curve for NCEH1 mutant vs wild-type samples in UCEC.

Open the UCEC breakdown →

Exploration