NCEH1

Across TCGA cell cohorts, NCEH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,016 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NCEH1-associated GO terms across cancer lineages are Regulation of macrophage fusion, Positive regulation of macrophage fusion, and Regulation of proteolysis. Each is linked with NCEH1 in more than 14 cancer types. Because this analysis shows association rather than direction, both NCEH1-to-partner and partner-to-NCEH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macrophage fusion grouped by NCEH1-low versus NCEH1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCEH1→partner) and Y-score (partner→NCEH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of macrophage fusion →	+0.247	+1.635	.001	<.001	3	15
BREAST	Positive regulation of macrophage fusion →	+0.247	+1.635	.001	<.001	3	15
OESOPHAGUS	Regulation of proteolysis →	+0.109	+1.541	.005	.001	3	14
BONE	Cellular response to environmental stimulus →	+0.049	+1.796	<.001	.002	3	13
LUNG_SCLC	Skeletal myofibril assembly →	+0.667	+1.281	<.001	<.001	3	13
SKIN	Low-density lipoprotein particle clearance →	+0.147	+0.850	<.001	.003	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,016 associations by consensus.

Regulation of macrophage fusion by NCEH1 expression — BREAST

Explore this box plot interactively →