NCDN

Across TCGA cell cohorts, NCDN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,532 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCDN-associated GO terms across cancer lineages are Cytosolic transport, Positive regulation of early endosome to late endosome transport, and Pre-miRNA processing. Each is linked with NCDN in more than 14 cancer types. Because this analysis shows association rather than direction, both NCDN-to-partner and partner-to-NCDN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by NCDN-low versus NCDN-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCDN→partner) and Y-score (partner→NCDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cytosolic transport →	+0.081	+1.018	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of early endosome to late endosome transport →	+0.138	+0.978	<.001	<.001	3	14
STOMACH	Pre-miRNA processing →	+0.135	+1.489	<.001	<.001	3	14
SKIN	Retrograde transport, endosome to Golgi →	+0.084	+0.999	<.001	<.001	3	14
LARGE_INTESTINE	Microtubule nucleation →	+0.118	+1.214	<.001	<.001	3	14
LARGE_INTESTINE	Microtubule polymerization →	+0.128	+1.291	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,532 associations by consensus.

Cytosolic transport by NCDN expression — SKIN

Explore this box plot interactively →