Across TCGA pan-cancer cohorts, NCCRP1 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NCCRP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NCCRP1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types NCCRP1 is over-expressed in tumor, although a few such as HNSC and CCRCC show the opposite, repressed pattern.

HNSC, LSCC, and CCRCC are the cancer types where NCCRP1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NCCRP1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	−2.139	<.001	11	view →
LSCC	All	III,IV	+1.472	<.001	9	view →
CCRCC	Male	III,IV	−1.251	<.001	9	view →
OV	All	All	−2.312	.037	2	view →
PDAC	All	All	+0.572	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: NCCRP1 RNA expression & survival · all NCCRP1 data types