NCBP3

Across TCGA patient cohorts, NCBP3 mutation is significantly associated with the RNA expression of many other genes, with 1,665 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCBP3-associated genes across cancer lineages are MIR5591, LINC02536, and RN7SKP181. Each is linked with NCBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCBP3-to-partner and partner-to-NCBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5591 grouped by NCBP3-low versus NCBP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCBP3→partner) and Y-score (partner→NCBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5591 →	+0.124	+3.055	<.001	.004	3	2
BLCA	LINC02536 →	+0.075	+5.497	.005	.004	3	2
STAD	RN7SKP181 →	+0.285	+4.691	<.001	.003	3	2
BLCA	OR10G3 →	+0.053	+5.788	<.001	.003	3	2
UCEC	IGHV1-69D →	+1.551	+1.541	<.001	.002	3	1
UCEC	LINC01943 →	+0.528	+1.787	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,665 associations by consensus.

MIR5591 by NCBP3 expression — UCEC

Explore this box plot interactively →