NCBP3

Across TCGA cell cohorts, NCBP3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NCBP3-associated genes across cancer lineages are AVP, BANF2, and TEX55. Each is linked with NCBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCBP3-to-partner and partner-to-NCBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by NCBP3-low versus NCBP3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCBP3→partner) and Y-score (partner→NCBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	BANF2 →	+0.096	+5.643	<.001	.002	3	1
CNS	TEX55 →	+0.037	+4.321	<.001	.009	3	1
SKIN	MYH1 →	+0.046	+3.920	<.001	.005	3	1
SKIN	MYH8 →	+0.033	+3.716	.004	.008	3	1
SKIN	MYH4 →	+0.022	+4.362	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

AVP by NCBP3 expression — BLOOD_Lymphoma

Explore this box plot interactively →