NCBP3

Across TCGA cell cohorts, NCBP3 mutation is significantly associated with the mutation status of many other genes, with 3,529 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCBP3-associated genes across cancer lineages are SYNGAP1, MPDZ, and PCDH9. Each is linked with NCBP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both NCBP3-to-partner and partner-to-NCBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SYNGAP1 grouped by NCBP3-low versus NCBP3-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCBP3→partner) and Y-score (partner→NCBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SYNGAP1 →	+4.614	+4.614	.006	.006	1	5
BLOOD_Leukemia	MPDZ →	+2.478	+3.544	.004	.004	1	5
BLOOD_Leukemia	PCDH9 →	+2.870	+3.347	.009	.009	1	5
OVARY	MYO18A →	+4.415	+4.977	.007	.007	1	5
LARGE_INTESTINE	MYLK →	+1.693	+3.506	.008	.008	1	4
LARGE_INTESTINE	MAST4 →	+1.693	+3.506	.008	.008	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,529 associations by consensus.

SYNGAP1 by NCBP3 expression — CNS

Explore this box plot interactively →