NCBP2

Across TCGA pan-cancer cohorts, NCBP2 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of NCBP2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NCBP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NCBP2 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, LIHC, and COAD are the cancer types where NCBP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NCBP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+1.425	<.001	12	view →
LIHC	Female	II,III,IV	+1.203	<.001	9	view →
COAD	Male	IV	+1.022	<.001	9	view →
LUSC	Female	All	+1.490	<.001	8	view →
STAD	Male	II,III,IV	+1.045	<.001	8	view →
LUAD	All	III,IV	+0.546	<.001	8	view →
BRCA	All	III,IV	+0.504	<.001	8	view →
BLCA	Female	III,IV	+0.720	.001	6	view →
CHOL	Male	All	+2.563	<.001	5	view →
KICH	All	All	−0.711	<.001	5	view →
ESCA	All	All	+0.887	.008	2	view →
READ	All	All	+0.832	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

NCBP2–HNSC

Open the HNSC breakdown →