NCAPGP2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NCAPGP2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated NCAPGP2 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher NCAPGP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NCAPGP2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and SARC show a favorable association.

PAAD, CHOL, and BRCA are the cancer types where NCAPGP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PAADOSTertileAll0.2150.563<.00154view →
CHOLOSTertileIII,IV0.0240.772.00854view →
BRCAOSTertileIV0.2330.755.03836view →
READDFSTertileIV0.0550.646<.00136view →
PRADDFSTertileAll0.8200.943<.00130view →
MESOOSTertileIV0.1550.624.00427view →
LIHCOSTertileIII,IV0.3100.694<.00115view →
THCAOSQuartileAll0.9440.990.0078view →
LUADOSMedianIII,IV0.3980.225.0098view →
BLCADFSTertileIII,IV0.4080.561.0426view →
OVOSMedianIV0.6740.811.0206view →
STADDFSQuartileAll0.1670.531.0093view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

NCAPGP2–PAAD (OS)

Kaplan–Meier survival curve for NCAPGP2 RNA-high vs -low samples in PAAD.

Open the PAAD breakdown →

Exploration