NCAPGP1

Across TCGA pan-cancer cohorts, NCAPGP1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of NCAPGP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NCAPGP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NCAPGP1 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

COAD, STAD, and LUSC are the cancer types where NCAPGP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NCAPGP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	All	+0.198	<.001	7	view →
STAD	Male	All	+0.145	.002	4	view →
LUSC	All	All	−0.079	.002	4	view →
ESCA	Male	All	+0.321	.018	3	view →
KICH	All	II,III,IV	+0.142	.012	3	view →
UCEC	All	All	+0.127	.012	2	view →
THCA	Female	All	−0.101	<.001	2	view →
LIHC	Male	All	+0.083	.001	2	view →
BRCA	All	All	+0.049	.039	2	view →
READ	All	All	+0.363	.026	1	view →
CHOL	All	All	+0.158	.048	1	view →
LUAD	All	All	+0.108	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

NCAPGP1–COAD

Open the COAD breakdown →