NCAPG2

Across TCGA patient cohorts, NCAPG2 mutation is significantly associated with the RNA expression of many other genes, with 3,298 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCAPG2-associated genes across cancer lineages are L3MBTL2, MDC1, and CENPP. Each is linked with NCAPG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NCAPG2-to-partner and partner-to-NCAPG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L3MBTL2 grouped by NCAPG2-low versus NCAPG2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPG2→partner) and Y-score (partner→NCAPG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	L3MBTL2 →	+0.299	+1.595	<.001	<.001	3	3
UCEC	MDC1 →	+0.501	+2.158	<.001	<.001	3	3
UCEC	CENPP →	+0.285	+1.776	<.001	<.001	3	3
UCEC	NRBF2P3 →	+0.073	+1.294	.001	.003	3	3
UCEC	CENPN-AS1 →	+0.272	+1.786	<.001	<.001	3	3
UCEC	CCDC116 →	+0.132	+1.715	.008	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,298 associations by consensus.

L3MBTL2 by NCAPG2 expression — UCEC

Explore this box plot interactively →