NCAPG2

Across TCGA cell cohorts, NCAPG2 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NCAPG2-associated genes across cancer lineages are FTMT, SPRR2F, and IFIT1B. Each is linked with NCAPG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCAPG2-to-partner and partner-to-NCAPG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTMT grouped by NCAPG2-low versus NCAPG2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPG2→partner) and Y-score (partner→NCAPG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	FTMT →	+0.065	+4.977	<.001	.002	3	1
SOFT_TISSUE	SPRR2F →	+0.176	+4.635	<.001	.003	3	1
LARGE_INTESTINE	IFIT1B →	+0.030	+3.145	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR13C9 →	+0.012	+5.266	<.001	.001	3	1
LUNG_SCLC	PRAMEF19 →	+0.013	+5.029	<.001	.006	3	1
CNS	OR8B4 →	+0.060	+6.357	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

FTMT by NCAPG2 expression — SOFT_TISSUE

Explore this box plot interactively →