NCAPG

Across TCGA pan-cancer cohorts, NCAPG mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NCAPG data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NCAPG mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NCAPG expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, LUAD, and OV are the cancer types where NCAPG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.891	0.503	<.001	21	view →
LUAD	DFS	Quartile	III,IV	1.000	0.375	.008	11	view →
OV	DFS	Median	All	0.871	1.000	.049	4	view →
PDAC	DFS	Median	II,III,IV	0.621	0.876	.027	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NCAPG–LSCC (DFS)

Open the LSCC breakdown →