NCAPD3

Across TCGA pan-cancer cohorts, NCAPD3 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NCAPD3 data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher NCAPD3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NCAPD3 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

DLBC, UCEC, and KICH are the cancer types where NCAPD3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Median	II,III,IV	0.172	0.949	<.001	27	view →
UCEC	DFS	Median	All	0.954	0.591	<.001	22	view →
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
BLCA	DFS	Median	IV	0.090	0.469	.009	12	view →
LGG	DFS	Median	All	0.249	0.728	.038	3	view →
STAD	DFS	Median	All	0.211	0.709	.015	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NCAPD3–DLBC (OS)

Open the DLBC breakdown →