NCAPD3

Across TCGA cell cohorts, NCAPD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,551 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NCAPD3-associated GO terms across cancer lineages are Meiotic chromosome condensation, DNA integrity checkpoint signaling, and Meiotic sister chromatid cohesion, centromeric. Each is linked with NCAPD3 in more than 19 cancer types. Because this analysis shows association rather than direction, both NCAPD3-to-partner and partner-to-NCAPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic chromosome condensation grouped by NCAPD3-low versus NCAPD3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPD3→partner) and Y-score (partner→NCAPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Meiotic chromosome condensation →	+0.210	+1.420	<.001	<.001	3	20
BONE	DNA integrity checkpoint signaling →	+0.102	+1.189	<.001	<.001	3	19
LARGE_INTESTINE	Meiotic sister chromatid cohesion, centromeric →	+0.190	+1.407	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.132	+1.992	<.001	<.001	3	19
BONE	Regulation of DNA replication →	+0.113	+1.323	.001	.004	3	19
BONE	Mitotic sister chromatid segregation →	+0.147	+1.480	.003	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,551 associations by consensus.

Meiotic chromosome condensation by NCAPD3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →