NCAPD3

Across TCGA cell cohorts, NCAPD3 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,699 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NCAPD3-associated GO terms across cancer lineages are Beta-arrestin-dependent dopamine receptor signaling pathway, Sodium ion transmembrane transport, and Polyol biosynthetic process. Each is linked with NCAPD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both NCAPD3-to-partner and partner-to-NCAPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Beta-arrestin-dependent dopamine receptor signaling pathway grouped by NCAPD3-low versus NCAPD3-high in SKIN.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPD3→partner) and Y-score (partner→NCAPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Beta-arrestin-dependent dopamine receptor signaling pathway →	+0.124	+1.393	.002	.007	3	2
SKIN	Sodium ion transmembrane transport →	+0.059	+1.393	.001	.007	3	2
SKIN	Polyol biosynthetic process →	+0.083	+1.393	.001	.007	3	2
SKIN	Succinyl-CoA metabolic process →	+0.117	+1.807	.006	.008	3	2
BLOOD_Lymphoma	Negative regulation of cytokine-mediated signaling pathway →	+0.119	+0.979	.001	.003	3	2
BLOOD_Lymphoma	NAD+ metabolic process →	+0.153	+1.259	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,699 associations by consensus.

Beta-arrestin-dependent dopamine receptor signaling pathway by NCAPD3 expression — SKIN

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