NCAPD2

Across TCGA cell cohorts, NCAPD2 mutation is significantly associated with the RNA expression of many other genes, with 523 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCAPD2-associated genes across cancer lineages are AOC3, AOC2, and DSG1. Each is linked with NCAPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCAPD2-to-partner and partner-to-NCAPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AOC3 grouped by NCAPD2-low versus NCAPD2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPD2→partner) and Y-score (partner→NCAPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AOC3 →	+0.665	+3.378	<.001	.005	3	2
BLOOD_Leukemia	AOC2 →	+0.695	+3.318	<.001	.005	3	2
BLOOD_Leukemia	DSG1 →	+0.086	+3.273	.004	<.001	3	2
BLOOD_Leukemia	CYP1A2 →	+0.023	+2.955	<.001	.007	3	2
BLOOD_Leukemia	EML5 →	+0.807	+3.259	.001	.006	3	2
SKIN	SPATA19 →	+0.119	+3.099	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 523 associations by consensus.

AOC3 by NCAPD2 expression — BLOOD_Leukemia

Explore this box plot interactively →