NCAPD2

Across TCGA cell cohorts, NCAPD2 mutation is significantly associated with the mutation status of many other genes, with 5,471 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCAPD2-associated genes across cancer lineages are ABCB6, ARFGEF2, and IFIH1. Each is linked with NCAPD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NCAPD2-to-partner and partner-to-NCAPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCB6 grouped by NCAPD2-low versus NCAPD2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPD2→partner) and Y-score (partner→NCAPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ABCB6 →	+4.969	+4.014	.008	.008	1	4
BLOOD_Leukemia	ARFGEF2 →	+3.665	+3.275	<.001	<.001	1	4
BLOOD_Leukemia	IFIH1 →	+3.080	+2.675	.004	.004	1	4
BLOOD_Leukemia	SPTBN1 →	+2.232	+2.282	.006	.006	1	4
BLOOD_Leukemia	MYORG →	+2.080	+2.169	.009	.009	1	4
BLOOD_Leukemia	PHACTR3 →	+5.665	+3.828	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,471 associations by consensus.

ABCB6 by NCAPD2 expression — BLOOD_Lymphoma

Explore this box plot interactively →