NCAM2

Across TCGA patient cohorts, NCAM2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,415 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NCAM2-associated genes across cancer lineages are LRRC4C, NAV3, and RASSF2. Each is linked with NCAM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NCAM2-to-partner and partner-to-NCAM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCAM2 versus LRRC4C in GBM, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAM2→partner) and Y-score (partner→NCAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LRRC4C →	+0.891	+0.522	<.001	<.001	3	5
BRCA	NAV3 →	+1.028	+0.807	<.001	<.001	3	5
GBM	RASSF2 →	+0.586	+0.525	.009	.006	3	4
LSCC	ARHGEF6 →	+0.888	+0.574	<.001	<.001	3	4
BRCA	PHLDB2 →	+1.077	+0.714	<.001	.001	3	4
GBM	PRKCB →	+0.960	+0.639	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,415 associations by consensus.

NCAM2 vs LRRC4C — GBM

Explore this scatter interactively →