NCAM2

Across TCGA cell cohorts, NCAM2 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible NCAM2-associated genes across cancer lineages are PRM2, PTCHD1, and CA6. Each is linked with NCAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCAM2-to-partner and partner-to-NCAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRM2 grouped by NCAM2-low versus NCAM2-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAM2→partner) and Y-score (partner→NCAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	PRM2 →	+0.053	+4.209	<.001	.006	3	2
BLOOD_Lymphoma	PTCHD1 →	+0.052	+4.606	.005	.001	3	2
SOFT_TISSUE	CA6 →	+0.122	+4.417	<.001	.004	3	1
SOFT_TISSUE	GSX1 →	+0.159	+4.882	<.001	.001	3	1
SOFT_TISSUE	GDF3 →	+0.604	+4.635	<.001	.003	3	1
SOFT_TISSUE	HELT →	+0.459	+4.882	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

PRM2 by NCAM2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →