NCAM1

Across TCGA cell cohorts, NCAM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,313 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NCAM1-associated GO terms across cancer lineages are Regulation of semaphorin-plexin signaling pathway, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with NCAM1 in more than 18 cancer types. Because this analysis shows association rather than direction, both NCAM1-to-partner and partner-to-NCAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of semaphorin-plexin signaling pathway grouped by NCAM1-low versus NCAM1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAM1→partner) and Y-score (partner→NCAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of semaphorin-plexin signaling pathway →	+1.630	+2.804	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.092	+1.015	.001	.007	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.105	+1.310	.001	.002	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.107	+1.310	<.001	.002	3	8
SOFT_TISSUE	Cellular respiration →	+0.047	+3.304	.002	<.001	3	8
SOFT_TISSUE	Ribose phosphate biosynthetic process →	+0.040	+2.611	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,313 associations by consensus.

Regulation of semaphorin-plexin signaling pathway by NCAM1 expression — OVARY

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