Across TCGA patient cohorts, NBR2 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBR2-associated genes across cancer lineages are MIR3691, MIR1273H, and MIR6726. Each is linked with NBR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBR2-to-partner and partner-to-NBR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBR2→partner) and Y-score (partner→NBR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR3691 →	+0.470	+5.669	<.001	.003	3	1
CESC	MIR1273H →	+0.468	+5.539	<.001	.004	3	1
CESC	MIR6726 →	+0.654	+7.164	<.001	<.001	3	1
CESC	RNU6-777P →	+0.417	+5.539	<.001	.004	3	1
CESC	TRAJ53 →	+0.715	+5.812	<.001	.003	3	1
CESC	RN7SKP213 →	+0.165	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

NBR2 survival (RNA) · tumor vs normal (RNA) · all NBR2 data types