Across TCGA patient cohorts, NBR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,176 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NBR1-associated proteins across cancer lineages are PIP4K2B, MTHFD2, and NPEPPS. Each is linked with NBR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NBR1-to-partner and partner-to-NBR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NBR1→partner) and Y-score (partner→NBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PIP4K2B →	+0.419	+0.951	<.001	<.001	3	5
BRCA	MTHFD2 →	-0.766	-0.696	<.001	<.001	3	5
BRCA	NPEPPS →	+0.412	+0.791	<.001	<.001	3	5
GBM	NSF →	+0.554	+0.334	<.001	<.001	3	5
CCRCC	SLC7A5 →	-1.235	-0.340	<.001	<.001	3	5
BRCA	TOM1L1 →	+0.676	+0.815	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,176 associations by consensus.

Exploration

NBR1 survival (RNA) · tumor vs normal (RNA) · all NBR1 data types