NBPF9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NBPF9 mutation is significantly associated with the RNA expression of many other genes, with 3,832 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF9-associated genes across cancer lineages are RNU6-131P, HPRT1P2, and SLC29A4P1. Each is linked with NBPF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF9-to-partner and partner-to-NBPF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-131P grouped by NBPF9-low versus NBPF9-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF9→partner) and Y-score (partner→NBPF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SARCRNU6-131P →+0.379+5.778<.001.00332
HNSCHPRT1P2 →+0.054+6.623<.001<.00132
CESCSLC29A4P1 →+0.027+4.384<.001.00832
COADMTND4LP2 →+0.095+4.136<.001.00832
UCECUEVLD →+0.397+2.724.008.00332
UCECTMEM251 →+0.513+3.480.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,832 associations by consensus.

RNU6-131P by NBPF9 expression — SARC

Box plot of RNU6-131P in NBPF9-low vs NBPF9-high samples in SARC.

Explore this box plot interactively →

Exploration