NBPF9

Across TCGA patient cohorts, NBPF9 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF9-associated genes across cancer lineages are ASNS, ATM, and PCNA. Each is linked with NBPF9 in more than 2 cancer types. Because this analysis shows association rather than direction, both NBPF9-to-partner and partner-to-NBPF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by NBPF9-low versus NBPF9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF9→partner) and Y-score (partner→NBPF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.548	+2.459	<.001	.018	3	3
UCEC	ATM →	-0.463	-2.415	.011	.003	3	3
UCEC	PCNA →	+0.219	+1.906	.011	.016	3	2
UCEC	c-Met_pY1235 →	+0.064	+1.906	.031	.016	3	2
UCEC	C-Raf →	+0.185	+2.415	.001	.003	3	2
UCEC	EGFR_pY1068 →	-0.207	-2.415	.041	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

ASNS by NBPF9 expression — UCEC

Explore this box plot interactively →