NBPF9

Across TCGA cell cohorts, NBPF9 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NBPF9-associated genes across cancer lineages are PPIAL4E, OR10H5, and FAM205A. Each is linked with NBPF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF9-to-partner and partner-to-NBPF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPIAL4E grouped by NBPF9-low versus NBPF9-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF9→partner) and Y-score (partner→NBPF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PPIAL4E →	+0.036	+5.643	<.001	.002	3	2
SKIN	OR10H5 →	+0.012	+4.977	<.001	.007	3	2
LARGE_INTESTINE	FAM205A →	+0.025	+3.614	<.001	.006	3	2
LIVER	PYDC1 →	+0.112	+4.459	<.001	.001	3	1
LIVER	C5orf67 →	+0.262	+3.977	.001	.006	3	1
CNS	UBQLN3 →	+0.006	+5.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

PPIAL4E by NBPF9 expression — LUNG_SCLC

Explore this box plot interactively →