Across TCGA patient cohorts, NBPF7 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF7-associated genes across cancer lineages are mTOR_pS2448, PDCD4, and C-Raf. Each is linked with NBPF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF7-to-partner and partner-to-NBPF7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF7→partner) and Y-score (partner→NBPF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.197	-3.000	.022	.037	3	2
UCEC	PDCD4 →	-0.687	-3.000	.011	.037	3	2
UCEC	C-Raf →	+0.250	+3.000	.002	.037	3	1
UCEC	Cyclin-E2 →	+0.274	+3.000	.004	.037	3	1
UCEC	Tuberin →	+0.328	+2.817	.035	.036	2	1
UCEC	Annexin-1 →	+0.634	+3.000	.037	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

NBPF7 survival (RNA) · tumor vs normal (RNA) · all NBPF7 data types