Across TCGA patient cohorts, NBPF6 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF6-associated genes across cancer lineages are GATA6, Caspase-8, and Rab25. Each is linked with NBPF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF6-to-partner and partner-to-NBPF6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF6→partner) and Y-score (partner→NBPF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GATA6 →	-0.221	-2.992	.013	.036	3	1
UCEC	Caspase-8 →	-0.377	-3.000	.006	.036	2	1
UCEC	Rab25 →	-0.368	-3.169	.043	.020	1	1
UCEC	TFRC →	+0.833	+3.169	.004	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

NBPF6 survival (RNA) · tumor vs normal (RNA) · all NBPF6 data types