NBPF3

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NBPF3 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NBPF3 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher NBPF3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NBPF3 expression acts as an unfavorable survival marker.

LIHC and UCEC are the cancer types where NBPF3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSMedianAll0.0980.777<.00112view →
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NBPF3–LIHC (OS)

Kaplan–Meier survival curve for NBPF3 mutant vs wild-type samples in LIHC.

Open the LIHC breakdown →

Exploration