NBPF3

Across TCGA cell cohorts, NBPF3 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NBPF3-associated genes across cancer lineages are OR10G6, WFDC11, and C3orf22. Each is linked with NBPF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF3-to-partner and partner-to-NBPF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G6 grouped by NBPF3-low versus NBPF3-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF3→partner) and Y-score (partner→NBPF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR10G6 →	+0.036	+5.285	<.001	.003	3	1
SKIN	WFDC11 →	+0.104	+4.977	<.001	.007	3	1
SKIN	C3orf22 →	+0.079	+5.415	<.001	.004	3	1
SKIN	RBMY1J →	+0.006	+4.977	<.001	.007	3	1
SKIN	OR5V1 →	+0.016	+4.977	<.001	.007	3	1
SKIN	GOLGA6L22 →	+0.006	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OR10G6 by NBPF3 expression — STOMACH

Explore this box plot interactively →