Q-omics provides the consensus-scored NBPF2P profile across patient tissues and cancer cell-line models. NBPF2P expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, NBPF2P is differentially expressed in 10, with the highest sampling consensus in THCA. Additionally, NBPF2P RNA expression shows 18,381 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight COAD, THCA, and THYM as cancer lineages where NBPF2P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NBPF2P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NBPF2P survival associations across molecular data types. NBPF2P RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NBPF2P RNA expression–survival associations across cancer types. High NBPF2P expression shows unfavorable associations in LGG, LUSC and HNSC, but favorable associations in COAD, KIRC and READ. The COAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for NBPF2P RNA expression.
This table summarizes NBPF2P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for NBPF2P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NBPF2P shows lower tumor expression in THCA, BRCA and KICH and higher tumor expression in LUAD, LUSC and COAD. The THCA box plot shows higher NBPF2P RNA expression in normal versus tumor tissue (log2 FC = −0.648, t-test p < 0.001).
This table shows molecular features associated with NBPF2P in patient tissues and cancer cell lines. In patient samples, NBPF2P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
