NBPF26

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NBPF26 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NBPF26-associated genes across cancer lineages are CLUHP5, OR5AC1, and MTATP6P29. Each is linked with NBPF26 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF26-to-partner and partner-to-NBPF26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLUHP5 grouped by NBPF26-low versus NBPF26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF26→partner) and Y-score (partner→NBPF26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCLUHP5 →+0.144+5.771<.001.00332
SKCMOR5AC1 →+0.064+7.816<.001.00831
SKCMMTATP6P29 →+0.364+7.816<.001.00831
UCECRNU6-173P →+0.614+5.937<.001.00231
UCECLINC01809 →+0.448+5.358<.001.00631
UCECRNU6-1101P →+1.080+4.982<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

CLUHP5 by NBPF26 expression — UCEC

Box plot of CLUHP5 in NBPF26-low vs NBPF26-high samples in UCEC.

Explore this box plot interactively →

Exploration