NBPF22P

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NBPF22P mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF22P-associated genes across cancer lineages are eIF4E, GAPDH, and JNK_pT183_Y185. Each is linked with NBPF22P in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF22P-to-partner and partner-to-NBPF22P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF22P→partner) and Y-score (partner→NBPF22P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeIF4E →+0.224+3.713.003<.00132
COADGAPDH →+0.648+2.820.013.03532
UCECJNK_pT183_Y185 →-0.188-1.807.001.02532
UCECmTOR_pS2448 →-0.116-1.680.031.04232
UCECMyosin-IIa_pS1943 →+0.152+1.293.041.03732
COADFASN →+0.584+3.008.003.01932
Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration