Across TCGA pan-cancer cohorts, NBPF21P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of NBPF21P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NBPF21P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NBPF21P is over-expressed in tumor, although a few such as KIRP and LUAD show the opposite, repressed pattern.

HNSC, KIRP, and LUAD are the cancer types where NBPF21P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NBPF21P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.043	.005	6	view →
KIRP	All	II,III,IV	−0.015	.009	5	view →
LUAD	Female	II,III,IV	−0.050	.012	2	view →
KIRC	Male	All	+0.014	.023	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: NBPF21P RNA expression & survival · all NBPF21P data types