Across TCGA pan-cancer cohorts, NBPF17P RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of NBPF17P’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NBPF17P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NBPF17P is over-expressed in tumor, although a few such as LUAD and UCEC show the opposite, repressed pattern.
HNSC, LUAD, and UCEC are the cancer types where NBPF17P tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NBPF17P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.