NBPF15

Across TCGA pan-cancer cohorts, NBPF15 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NBPF15 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NBPF15 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NBPF15 expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

UCEC, LUSC, and SKCM are the cancer types where NBPF15 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LUSC	DFS	Median	All	1.000	0.382	.025	4	view →
SKCM	OS	Median	III,IV	0.233	0.705	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NBPF15–UCEC (OS)

Open the UCEC breakdown →