NBPF15

Across TCGA cell cohorts, NBPF15 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NBPF15-associated genes across cancer lineages are LHCGR, PRLHR, and LMX1A. Each is linked with NBPF15 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF15-to-partner and partner-to-NBPF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LHCGR grouped by NBPF15-low versus NBPF15-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF15→partner) and Y-score (partner→NBPF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	LHCGR →	+0.030	+4.350	.007	.005	3	2
BREAST	PRLHR →	+0.017	+3.672	<.001	.006	3	1
BREAST	LMX1A →	+0.021	+4.285	<.001	.005	3	1
BREAST	HTR1E →	+0.301	+3.807	.007	.006	3	1
BREAST	KRTAP11-1 →	+0.383	+3.963	<.001	.003	3	1
BREAST	KRTAP8-1 →	+0.090	+4.196	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

LHCGR by NBPF15 expression — BLOOD_Lymphoma

Explore this box plot interactively →