NBPF14

Across TCGA patient cohorts, NBPF14 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF14-associated genes across cancer lineages are RNU2-47P, RNU6-211P, and RNA5SP414. Each is linked with NBPF14 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF14-to-partner and partner-to-NBPF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-47P grouped by NBPF14-low versus NBPF14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF14→partner) and Y-score (partner→NBPF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU2-47P →	+0.189	+5.475	<.001	.001	3	2
BLCA	RNU6-211P →	+0.238	+7.640	<.001	.009	3	2
UCEC	RNA5SP414 →	+1.040	+3.255	<.001	.003	3	2
UCEC	RNA5SP412 →	+0.944	+2.967	<.001	.007	3	2
UCEC	OR6K3 →	+0.142	+3.982	<.001	<.001	3	1
UCEC	RNU6-657P →	+0.262	+4.137	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

RNU2-47P by NBPF14 expression — UCEC

Explore this box plot interactively →