NBPF14

Across TCGA cell cohorts, NBPF14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,144 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NBPF14-associated GO terms across cancer lineages are Negative regulation of calcineurin-mediated signaling, Establishment of protein localization to plasma membrane, and Negative regulation of calcineurin-NFAT signaling cascade. Each is linked with NBPF14 in more than 9 cancer types. Because this analysis shows association rather than direction, both NBPF14-to-partner and partner-to-NBPF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcineurin-mediated signaling grouped by NBPF14-low versus NBPF14-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF14→partner) and Y-score (partner→NBPF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of calcineurin-mediated signaling →	+0.197	+0.935	<.001	<.001	3	10
BONE	Establishment of protein localization to plasma membrane →	+0.127	+0.965	<.001	.003	3	10
BONE	Negative regulation of calcineurin-NFAT signaling cascade →	+0.197	+0.935	<.001	<.001	3	10
SOFT_TISSUE	Maintenance of protein localization in organelle →	+0.091	+0.742	<.001	<.001	3	10
BONE	Vesicle-mediated transport to the plasma membrane →	+0.087	+0.984	<.001	.002	3	10
CNS	Negative regulation of cytokine production →	+0.049	+0.936	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,144 associations by consensus.

Negative regulation of calcineurin-mediated signaling by NBPF14 expression — BONE

Explore this box plot interactively →