NBPF12

Across TCGA patient cohorts, NBPF12 mutation is significantly associated with the RNA expression of many other genes, with 2,621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF12-associated genes across cancer lineages are OR4A18P, CRYBB2P1, and DLST. Each is linked with NBPF12 in more than 2 cancer types. Because this analysis shows association rather than direction, both NBPF12-to-partner and partner-to-NBPF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4A18P grouped by NBPF12-low versus NBPF12-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF12→partner) and Y-score (partner→NBPF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR4A18P →	+0.039	+4.505	<.001	.009	3	3
UCEC	CRYBB2P1 →	+0.407	+2.294	<.001	<.001	3	2
UCEC	DLST →	+0.341	+1.754	.006	.001	3	2
UCEC	EXOSC8 →	+0.309	+1.776	.004	<.001	3	2
UCEC	IBA57 →	+0.332	+1.797	.001	<.001	3	2
UCEC	SHMT2 →	+0.422	+1.769	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,621 associations by consensus.

OR4A18P by NBPF12 expression — HNSC

Explore this box plot interactively →