NBPF12

Across TCGA cell cohorts, NBPF12 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NBPF12-associated genes across cancer lineages are R3HDML, HS3ST2, and PIP. Each is linked with NBPF12 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF12-to-partner and partner-to-NBPF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, R3HDML grouped by NBPF12-low versus NBPF12-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF12→partner) and Y-score (partner→NBPF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	R3HDML →	+0.016	+4.984	<.001	.002	3	1
BLOOD_Leukemia	HS3ST2 →	+0.831	+4.339	<.001	.002	3	1
BLOOD_Leukemia	PIP →	+0.060	+3.705	<.001	.007	3	1
BLOOD_Leukemia	OR56A4 →	+0.009	+3.874	<.001	.005	3	1
BLOOD_Leukemia	KRTAP5-1 →	+0.143	+3.855	<.001	.007	3	1
BLOOD_Leukemia	BOD1L2 →	+0.027	+4.691	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

R3HDML by NBPF12 expression — BLOOD_Leukemia

Explore this box plot interactively →