NBN

Across TCGA patient cohorts, NBN RNA expression is significantly associated with the protein abundance of many other proteins, with 7,529 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NBN-associated proteins across cancer lineages are RIPK2, YTHDF3, and OTUD6B. Each is linked with NBN in more than 5 cancer types. Because this analysis shows association rather than direction, both NBN-to-partner and partner-to-NBN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NBN versus RIPK2 in OV, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NBN→partner) and Y-score (partner→NBN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RIPK2 →	+0.489	+0.729	<.001	.001	2	6
OV	YTHDF3 →	+0.365	+0.824	<.001	<.001	3	4
OV	OTUD6B →	+0.503	+0.747	<.001	.001	3	4
BRCA	TCEA1 →	+0.291	+0.626	.001	.001	3	4
OV	POP1 →	+0.305	+0.809	<.001	<.001	3	3
LSCC	RBM12B →	+0.177	+0.338	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,529 associations by consensus.

NBN vs RIPK2 — OV

Explore this scatter interactively →