NBN

Across TCGA patient cohorts, NBN protein abundance is significantly associated with the protein abundance of many other proteins, with 19,496 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NBN-associated proteins across cancer lineages are RAD50, BCLAF1, and CCAR1. Each is linked with NBN in more than 9 cancer types. Because this analysis shows association rather than direction, both NBN-to-partner and partner-to-NBN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NBN versus RAD50 in OV, with a Pearson correlation of 0.67.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NBN→partner) and Y-score (partner→NBN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RAD50 →	+0.467	+0.364	<.001	<.001	3	10
GBM	BCLAF1 →	+0.349	+0.313	<.001	<.001	3	9
GBM	CCAR1 →	+0.247	+0.275	<.001	<.001	3	9
COAD	MRE11 →	+0.407	+0.304	<.001	<.001	3	9
GBM	RBM12B →	+0.325	+0.323	<.001	<.001	3	9
GBM	RBM25 →	+0.338	+0.293	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,496 associations by consensus.

NBN vs RAD50 — OV

Explore this scatter interactively →