NBL1

Across TCGA pan-cancer cohorts, NBL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NBL1 data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NBL1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NBL1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where NBL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.918	1.000	.004	28	view →
PDAC	OS	Quartile	All	0.277	0.488	.019	19	view →
LSCC	DFS	Median	All	0.453	0.868	.020	7	view →
HNSC	OS	Tertile	All	0.820	0.615	.024	3	view →
CCRCC	OS	Median	All	0.514	1.000	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NBL1–LUAD (OS)

Open the LUAD breakdown →