NBL1

Across TCGA patient cohorts, NBL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,325 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NBL1-associated proteins across cancer lineages are ITGB5, DAB2_S723, and TAGLN. Each is linked with NBL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both NBL1-to-partner and partner-to-NBL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NBL1 versus ITGB5 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NBL1→partner) and Y-score (partner→NBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ITGB5 →	+0.642	+1.110	<.001	.001	3	9
LSCC	DAB2_S723 →	+0.808	+0.681	<.001	<.001	3	8
UCEC	TAGLN →	+1.072	+1.244	<.001	<.001	3	8
OV	COPZ2 →	+0.886	+1.407	<.001	<.001	3	8
OV	FAP →	+0.910	+1.229	<.001	<.001	3	8
GBM	FBLN1_S147 →	+1.459	+0.966	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,325 associations by consensus.

NBL1 vs ITGB5 — BRCA

Explore this scatter interactively →